Investigating the interplay of inflammation, angiogenesis and metabolic dysfunction in the retina to find novel therapeutic avenues for age-related macular degeneration (AMD)
“Research is formalized curiosity. It is poking and prying with a purpose.”
—Zora Neale Hurston
learn about our research interests
Current Research Projects
The Shu Lab is dedicated to unraveling the mysteries of age-related macular degeneration (AMD) and eradicating blindness caused by this condition. Employing a multidisciplinary approach encompassing cell biology, molecular biology, biochemistry, bioinformatics, and clinical imaging, our lab’s mission centres on understanding AMD’s pathogenesis. However, we don’t stop at comprehension; our ultimate aim is to develop novel drugs and identify fresh drug targets, ultimately striving for a cure. We believe in the transformative power of science to enhance lives and offer hope to those affected by AMD. Join us in our relentless pursuit of a brighter future, where blindness becomes a thing of the past.
Project 1: Mitochondrial Dysfunction in AMD
This project is dedicated to exploring the pivotal role of mitochondria in age-related macular degeneration (AMD). We investigate how mitochondria and metabolism undergo changes during AMD and their significant contribution to the disease’s progression. Our mission is to uncover potential drug targets capable of blocking these detrimental changes. Through cutting-edge research, we strive to develop pharmaceutical interventions that can effectively halt AMD’s advancement, offering new hope to those affected by this vision-threatening condition. Join us in our journey to illuminate the role of mitochondria in AMD and develop novel strategies for its control.
Project 2: Gene Expression Signatures in AMD
In this project, we delve into intricate world of transcriptomics, aiming to uncover the molecular secrets of age-related macular degeneration (AMD), specifically focusing on geographic atrophy and choroidal neovascularization. Through cutting-edge transcriptomics and proteomics approaches, we meticulously identify gene expression patterns that play a pivotal role in the pathogenesis of AMD. Exploring the crucial molecular pathways, including mitochondrial functions, metabolic pathways, and extracellular cellular matrix reorganization, will shed light on the complex interplay of these elements in AMD progression. This project not only enhances our understanding of AMD but also opens doors to potential therapeutic interventions by targeting these pathways. Join us as we decode the genetic underpinnings of AMD cytokines, working towards innovative solutions to combat this sight-threatening condition.
Meet our Exceptional Team of Scientists
At the heart of our mission to combat age-related macular degeneration (AMD) is our exceptional team of scientists. We take pride in our diverse and talented group, comprising individuals from various backgrounds and career stages, ranging from high school students to undergraduates and graduate students and postdocs. Each member brings a unique perspective and skill set, contributing to the vibrant tapestry of our research endeavors.
Our collaborative spirit drives innovation and fuels our quest to understand AMD better, develop novel treatments, and ultimately work towards a world without blindness caused by this condition. Together, we share a common passion for scientific discovery and a commitment to making a difference in the lives of those affected by AMD.
Read more about our lab members here.
Join Our Growing Team
As we continue to expand our efforts in unraveling the complexities of AMD, we are actively seeking new talent to join our dynamic team. If you share our enthusiasm for scientific exploration and aspire to contribute to groundbreaking research, we invite you to explore opportunities with us.
Whether you’re a seasoned researcher or just embarking on your scientific journey, we believe in nurturing talent and fostering growth. Join us in our mission to make strides in AMD research, develop innovative treatments, and create a brighter future for individuals facing the threat of blindness.
Stay tuned for updates on our recruitment efforts and exciting opportunities to be a part of the Shu Lab family. Together, we can bring clarity to the mysteries of AMD and offer hope to those in need.
Where Science Meets Serenity
Nestled in Sydney, Australia, the Shu Lab thrives at the University of New South Wales (UNSW) in the School of Optometry and Vision Science. Our lab’s setting is more than just location; it’s an inspiration. With Sydney’s stunning landscapes, nearby pristine beaches, and fantastic climate, we enjoy a unique blend of work and leisure. The sun-soaked days and mild winters make Sydney an ideal environment for our research team. The city’s multicultural energy and intellectual diversity enrich our work, creating a dynamic and rewarding experience at the intersection of science and serenity. Join us, where science meets the beauty of Sydney.
latest news
Stay informed and connected with the latest developments, breakthroughs, and milestones from the Shu Lab. Our commitment to advancing research on age-related macular degeneration (AMD) is ever-evolving, and we’re excited to share our progress with you.
Explore our news section to discover:
- Research Insights: Get a glimpse into our ongoing studies, findings, and scientific discoveries related to AMD. We provide detailed insights into the cutting-edge research projects our team is engaged in.
- Publication Highlights: Stay up-to-date with our published research articles, papers, and contributions to the field of AMD. We take pride in sharing our work with the scientific community and the public.
- Team Achievements: Celebrate the accomplishments of our dedicated team members, from awards and recognitions to notable achievements in their scientific careers.
- Community Engagement: Learn about our involvement in community outreach, educational programs, and events aimed at raising awareness about AMD and vision-related issues.
- Upcoming Events: Stay in the loop about upcoming conferences, seminars, and presentations where you can connect with our researchers and learn more about our work.
We invite you to explore our latest news section regularly to stay informed about our efforts to understand, treat, and ultimately prevent AMD. Your support and interest are instrumental in driving our mission forward, and we look forward to sharing our journey with you.
Latest News from the Shu lab:
-
Celebrating Kelvin Huang’s Achievement: The H.C. & M.E. Porter Memorial Endowed Award
In a remarkable acknowledgment of academic excellence and dedication to vision science, Kelvin Huang, an honours student from the Retinal Research Group led by Dr. Daisy Shu, has been awarded the prestigious UGCA1035 H.C. & M.E. Porter Memorial Endowed Award. This $8,000 scholarship is granted to students demonstrating outstanding academic merit and commitment within the…
-
Protected: ASIP2023 Conference in Salt Lake City, Utah
There is no excerpt because this is a protected post.
-
Dr. Daisy Shu Shines at BrightFocus Foundation’s Congressional Briefing for Health Equity
In a significant step toward promoting health equity and advancing research, Dr. Daisy Shu, a distinguished scientist, was a prominent guest at the recent BrightFocus Foundation Congressional Briefing on Health Equity. The event took place as part of the organization’s 50th-anniversary celebration, aptly tagged “Bold Research for a Better Tomorrow.” Watch the YouTube recording of…
We are growing our research team
join us in the fight against blindness
Are you passionate about making a meaningful impact in the field of age-related macular degeneration (AMD)? At the Shu Lab, we welcome collaborations and are actively seeking individuals interested in joining our dedicated research team.
Collaborations: We believe that collaboration is the key to innovation. If you are a researcher, scientist, or organization with aligned interests in AMD research, we invite you to reach out and explore collaborative opportunities. Together, we can amplify our efforts and drive progress in understanding, treating, and ultimately preventing AMD.
Research Team: If you are an aspiring scientist, a student, or a seasoned researcher looking to contribute to our mission, we encourage you to connect with us. Our lab is open to individuals from diverse backgrounds and career stages, from high school students to graduates. Whether you’re interested in hands-on laboratory work, data analysis, or project management, there may be a place for you on our dynamic team.
Get in Touch: To discuss how you can get involved, collaborate, or join our research team, please don’t hesitate to reach out. Your expertise, enthusiasm, and dedication can be a driving force in our quest to combat AMD and offer hope to those affected by this condition.
Together, we can make a difference. Contact us today, and let’s explore the exciting possibilities of working together to advance AMD research and improve lives.
Shu Lab - Retinal Research Group, UNSW SOVS 